Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 5/20 | 0.37 |
| ▸ | CES1 | P23141 | 5/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340356 | 0.77 | TSHR (0.33) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL434505 | 0.75 | TSHR (0.46) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL2788908 | 0.73 | LMNA (0.31) | TSHRLMNA | |
| SCHEMBL11418684 | 0.72 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL681730 | 0.72 | — | — | |
| SCHEMBL10401717 | 0.72 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL10401632 | 0.72 | TSHR (0.43) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL3676139 | 0.72 | TSHR (0.43) | TSHRLMNATHRBCES2CES1 | |
| SCHEMBL626348 | 0.72 | — | — | |
| Pentane SCHEMBL15266712 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744605-A | ANNULATION; CYCLIZATION | UNIVERSITY OF PITTSBURGH (US) | 1998-04-28 | — | — | US | claimed |
| US-5210365-A | Molybdenum or rhenium oxide on oxide support | SHELL OIL COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5114899-A | Molybdenum and/or rhenium supported on oxide and promoted with silane and/or disilane compound | SHELL OIL COMPANY (US) | 1992-05-19 | — | — | US | disclosed |
| US-4363925-A | PALLADIUM COMPLEX AND A PHOSPHINE OR PHOSPHITE CATALYZED REACTION OF A DISILANE AND AN AROMATIC HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1982-12-14 | — | — | US | disclosed |