Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664898 | 0.77 | TSHR (0.46) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL348204 | 0.71 | TSHR (0.40) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL9650624 | 0.71 | TSHR (0.40) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL135253 | 0.71 | — | — | |
| SCHEMBL187377 | 0.71 | TSHR (0.40) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL707007 | 0.69 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL446925 | 0.69 | — | — | |
| SCHEMBL704342 | 0.69 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL702967 | 0.69 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL704794 | 0.69 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325248-B1 | A process for the chlorodephenylation of phenylsilanes | DOW CORNING (US) | 1994-06-15 | — | — | EP | disclosed |
| US-4855471-A | Process for the chlorodephenylation of phenyldisilanes | DOW CORNING CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0325248-A2 | A process for the chlorodephenylation of phenylsilanes | DOW CORNING CORPORATION (US) | 1989-07-26 | — | — | EP | disclosed |