Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523243 | 0.90 | GPR119 (0.47) | MAPTTP53GAAKMT2AMEN1 | |
| SCHEMBL8664948 | 0.84 | TP53 (0.48) | MAPTTP53GAAKMT2ALMNA | |
| SCHEMBL8666467 | 0.82 | SMN1; SMN2 (0.45) | MAPTTP53GAAKMT2AMEN1 | |
| SCHEMBL8663363 | 0.80 | MAPT (0.51) | MAPTTP53KMT2AMEN1LMNA | |
| SCHEMBL7351054 | 0.78 | SMN1; SMN2 (0.50) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL8468356 | 0.78 | MAPT (0.40) | MAPTTP53GAAKMT2AMEN1 | |
| SCHEMBL6192490 | 0.76 | GPR119 (0.62) | MAPTLMNAGPR119 | |
| SCHEMBL8325925 | 0.75 | THRB (0.44) | MAPTGAAKMT2APTPN2PTPN1 | |
| SCHEMBL13334570 | 0.74 | ESR2 (0.50) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL15824735 | 0.74 | GPR119 (0.58) | MAPTTP53GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |