Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19656309 | 0.73 | DGAT1 (0.38) | GAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1576184 | 0.71 | CA14 (0.40) | CXCR2SMN1; SMN2ALDH1A1F2PRSS1 | |
| SCHEMBL8671326 | 0.71 | ALDH1A1 (0.36) | GAAALDH1A1 | |
| SCHEMBL21801671 | 0.71 | ALDH1A1 (0.36) | CXCR2ALDH1A1 | |
| SCHEMBL21801399 | 0.71 | ALDH1A1 (0.36) | CXCR2ALDH1A1 | |
| SCHEMBL2832124 | 0.71 | ALDH1A1 (0.36) | CXCR2ALDH1A1 | |
| SCHEMBL2797628 | 0.71 | CA14 (0.41) | CXCR2SMN1; SMN2F2PRSS1PRSS2 | |
| SCHEMBL16584183 | 0.71 | CA14 (0.41) | CXCR2SMN1; SMN2F2PRSS1PRSS2 | |
| SCHEMBL2598240 | 0.71 | CA14 (0.41) | CXCR2SMN1; SMN2F2PRSS1PRSS2 | |
| SCHEMBL18260609 | 0.69 | CA2 (0.32) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750778-A | FLUOROALKANOIC ACIDS AND DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| EP-0468681-A1 | Alfa-fluorocarboxylic acid derivatives as intermediates for the preparation of fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |