SCHEMBL2832124

SCHEMBL2832124

CC(OS(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21801671 1.00 ALDH1A1 (0.36) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL21801399 1.00 ALDH1A1 (0.36) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL13047233 0.83 ALDH1A1 (0.35) ALDH1A1CA1CA2CA9
SCHEMBL575704 0.79 CA1 (0.33) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL22588839 0.79 ALDH1A1 (0.39) ALDH1A1CA1CA2CA9
SCHEMBL14779233 0.79 CA1 (0.43) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL778573 0.79 ALDH1A1 (0.46) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL17447776 0.77 ALDH1A1 (0.38) ALDH1A1CA1CA2CA9
SCHEMBL778307 0.77 CA1 (0.32) ALDH1A1CA1CA2CA9CXCR2
SCHEMBL1759309 0.77 CA1 (0.32) ALDH1A1CA1CA2CA9CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240363910-A1 ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE CONTAINING SAME NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2024-10-31 US claimed
WO-2023130423-A1 ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE COMPRISING SAME 宁德新能源科技有限公司 2023-07-13 WO claimed
US-20260116891-A1 Oxazepin Derivative TEIJIN PHARMA LTD (JP) 2026-04-30 US disclosed
EP-4727935-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF Lynk Pharmaceuticals Co. Ltd. (CN) 2026-04-22 EP disclosed
US-20260049092-A1 ANTIBACTERIAL COMPOUNDS BLACKSMITH MEDICINES INC (US) 2026-02-19 US disclosed
US-20250214991-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS 2025-07-03 US disclosed
WO-2025137329-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA, INC (US) 2025-06-26 WO disclosed
EP-4568955-A1 ANTIBACTERIAL COMPOUNDS Blacksmith Medicines, Inc. (US) 2025-06-18 EP disclosed
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO LTD (CN) 2025-04-10 US disclosed
EP-4512811-A1 OXAZEPINE DERIVATIVE Teijin Pharma Limited (JP) 2025-02-26 EP disclosed
WO-2025030117-A1 FERROPTOSIS INDUCERS ARPEGGIO BIOSCIENCES, INC. (US) 2025-02-06 WO disclosed
WO-2006079467-A1 PHENYL METHANONE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER 1 INHIBITORS F. HOFMANN-LA ROCHE AG (CH) 2006-08-03 WO disclosed
US-20060167023-A1 Substituted phenyl methanones HOFFMANN-LA ROCHE INC. 2006-07-27 US disclosed
US-20060167009-A1 Monocyclic substituted phenyl methanones F. HOFFMANN-LA ROCHE AG (CH) 2006-07-27 US disclosed
WO-2006077026-A1 2, 5-DISUBSTITUTED PHENYL METHANONE DERIVATIVES AS GLYCINE TRANSPORTER 1 (GLYT-I) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRY DISORDERS F.HOFFMANN-LA ROCHE AG (CH) 2006-07-27 WO disclosed
US-20060160788-A1 Substituted phenyl methanone derivatives HOFFMANN-LA ROCHE INC. 2006-07-20 US disclosed
WO-2006072436-A1 [4-(HETEROARYL) PIPERAZIN-1-YL]-(2,5-SUBSTITUTED -PHENYL)METHANONE DERIVATIVES AS GLYCINE TRANSPORTER 1 (GLYT-1) INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS F. HOFFMANN-LA ROCHE AG (CH) 2006-07-13 WO disclosed
EP-1656361-A1 PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2006-05-17 EP disclosed
US-20050209241-A1 Benzoyl-piperazine derivatives HOFFMANN-LA ROCHE INC. 2005-09-22 US disclosed
WO-2005014563-A1 PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209241-A1 Benzoyl-piperazine derivatives SLC1A2, SLC18A2, SLC6A7 ALDH1A1 1436/4885CA1 4221/4885CA2 3258/4885
US-20060160788-A1 Substituted phenyl methanone derivatives SLC6A5, SLC6A1, SLC1A1 ALDH1A1 734/4885CA1 1533/4885CA2 3180/4885
US-20060167023-A1 Substituted phenyl methanones SLC6A7, SLC1A1, SLC26A3 ALDH1A1 1405/4885CA1 2299/4885CA2 2621/4885
US-20260049092-A1 ANTIBACTERIAL COMPOUNDS H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, FPR1 ALDH1A1 3250/4885CA1 3523/4885CA2 911/4885
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF TYK2, JAK2, JAK1 ALDH1A1 4805/4885CA1 4820/4885CA2 4261/4885
US-20250214991-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS IKZF1, IKZF2, IKZF3 ALDH1A1 3438/4885CA1 4707/4885CA2 3770/4885
US-20060167009-A1 Monocyclic substituted phenyl methanones SLC1A2, SULT2A1, SLC6A5 ALDH1A1 744/4885CA1 791/4885CA2 2023/4885
US-20260116891-A1 Oxazepin Derivative HCRTR2, HCRTR1, OXTR ALDH1A1 754/4885CA1 765/4885CA2 531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.