Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12988880 | 0.85 | NPSR1 (0.66) | HPGDNPSR1MCOLN3ALDH1A1CES2 | |
| SCHEMBL154606 | 0.81 | TRPM8 (0.53) | HPGDNPSR1ALDH1A1CES2CES1 | |
| SCHEMBL8079678 | 0.80 | NPSR1 (0.60) | HPGDNPSR1MCOLN3ALDH1A1CES2 | |
| SCHEMBL11780823 | 0.79 | NPSR1 (0.46) | HPGDNPSR1MCOLN3ALDH1A1CES2 | |
| SCHEMBL7563094 | 0.78 | KDM4E (0.49) | HPGDALDH1A1LMNAHTTMEN1 | |
| SCHEMBL21541337 | 0.77 | ALDH1A1 (0.50) | HPGDNPSR1MCOLN3ALDH1A1CES2 | |
| SCHEMBL8467615 | 0.76 | ALDH1A1 (0.54) | HPGDNPSR1ALDH1A1CES2CES1 | |
| SCHEMBL12302001 | 0.75 | ALDH1A1 (0.48) | HPGDNPSR1MCOLN3ALDH1A1CES2 | |
| SCHEMBL4711272 | 0.75 | ALDH1A1 (0.59) | HPGDNPSR1ALDH1A1CES2CES1 | |
| SCHEMBL30491049 | 0.75 | MLYCD (0.50) | HPGDNPSR1ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627452-B1 | UV-absorbing polyurethanes and polyesters | CIBA GEIGY AG (CH) | 1998-12-09 | — | — | EP | disclosed |
| US-5459222-A | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY CORPORATION | 1995-10-17 | — | — | US | disclosed |
| EP-0627452-A1 | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY AG (CH) | 1994-12-07 | — | — | EP | disclosed |