SCHEMBL154606

SCHEMBL154606

CC(O)N(C(=O)c1ccccc1)C(C)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 5/20 0.53
NPSR1 Q6W5P4 2/20 0.45
NR1I2 O75469 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
PGR P06401 1/20 0.44
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
HTR2A P28223 1/20 0.44
HRH1 P35367 1/20 0.44
KCNH2 Q12809 1/20 0.44
HSD11B1 P28845 1/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
XBP1 P17861 1/20 0.44
ATM Q13315 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MLYCD O95822 1/20 0.44
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458409 0.84 NPSR1 (0.59) TRPM8NPSR1NR1I2ALDH1A1HPGD
Hydrochloric Acid SCHEMBL31125741 0.83 NPSR1 (0.57) TRPM8NPSR1NR1I2ALDH1A1HPGD
Hydrochloric Acid SCHEMBL3759428 0.83 NPSR1 (0.57) TRPM8NPSR1NR1I2ALDH1A1HPGD
SCHEMBL6831416 0.81 NOD2 (0.48) TRPM8NPSR1ALDH1A1HPGDPGR
SCHEMBL8665698 0.81 HPGD (0.50) TRPM8NPSR1ALDH1A1HPGDLMNA
SCHEMBL1477108 0.79 NPSR1 (0.54) TRPM8NPSR1NR1I2ALDH1A1HPGD
SCHEMBL7563094 0.79 KDM4E (0.49) ALDH1A1HPGDLMNAMLYCDNAPRT
SCHEMBL3278792 0.78 HSD11B1 (0.48) TRPM8NPSR1ALDH1A1HPGDPGR
SCHEMBL4379528 0.78 TRPM8 (0.49) TRPM8NPSR1NR1I2ALDH1A1HPGD
SCHEMBL11783815 0.78 TRPM8 (0.53) TRPM8NPSR1NR1I2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060115536-A1 Glycerin based synthesis of silver nanoparticles and nanowires BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-06-01 US claimed
US-20030119931-A1 Novel spiroorthocarbonates THE CURATORS OF THE UNIVERSITY OF MISSOURI 2003-06-26 US claimed
US-20020013380-A1 PHOTOPOLYMERIZABLE VINYL ETHER BASED MONOMERIC FORMULATIONS AND POLYMERIZABLE COMPOSITIONS WHICH MAY INCLUDE CERTAIN NOVEL SPIROORTHOCARBONATES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-01-31 US claimed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12311037-B2 Dental composition containing a resorcinol or catechol moiety containing component and use thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-27 US disclosed
US-20250114283-A1 Dental Composition Containing a Resorcinol or Catechol Moiety Containing Component and Use Thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-04-10 US disclosed
EP-4514304-A1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-03-05 EP disclosed
WO-2023209463-A1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-02 WO disclosed
CN-108189525-B Method for improving adhesive property of composite film 昆明理工大学 2020-01-10 CN disclosed
EP-2741728-B1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2019-06-26 EP disclosed
EP-2670375-B1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2019-05-01 EP disclosed
US-4503211-A GOOD POT LIFE MINNESOTA MINING AND MANUFACTURING CO. (US) 1985-03-05 US disclosed
EP-0084406-A1 Ophthalmic device comprising a polymer of a telechelic perfluoropolyether MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed
US-4324679-A INCLUSION OF UNSATURATED COMPOUND TO REACT WITH ORGANOSULFUR DECOMPOSITION PRODUCTS OF PHOTOINITIATOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-04-13 US disclosed
US-4318766-A CURED COATING USING IODONIUM OR SULFONIUM PHOTOINITIATOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-03-09 US disclosed
US-4256828-A SULFONIUM OR IODONIUM COMPLEX SALTS AS PHOTOINITIATORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-03-17 US disclosed
US-4231951-A TRIARYLSULFONIUM HEXAFLUOROANTIMONATE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-11-04 US disclosed
US-4218531-A AROMATIC SULFONIUM COMPLEX SALT PHOTOINITIATOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-08-19 US disclosed
US-4173476-A TRIARYLULFONIUM HEXAFLUOROANTIMONATE OR HYDROXYPENTAFLUOROANTIMONATE, PHOTOPOLYMERIZATION OF EPOXIDE MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-11-06 US disclosed
US-4115295-A EPOXIDE FUNCTIONAL, HYDROXY FUNCTIONAL, DIELECTRICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12311037-B2 Dental composition containing a resorcinol or catechol moiety containing component and use thereof RDX, RECQL, RHOC TRPM8 3529/4885NPSR1 4287/4885NR1I2 615/4885
US-20250114283-A1 Dental Composition Containing a Resorcinol or Catechol Moiety Containing Component and Use Thereof RDX, RECQL, RABGGTB TRPM8 3547/4885NPSR1 4254/4885NR1I2 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.