Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713186 | 0.96 | DRD2 (0.36) | DRD2MCHR1ALDH1A1RAB9ACKS1B | |
| SCHEMBL8665883 | 0.89 | NPSR1 (0.37) | DRD2MCHR1UTS2RCCR3MEN1 | |
| SCHEMBL8665520 | 0.88 | CCR3 (0.42) | DRD2KDM5ACCR3 | |
| SCHEMBL8666099 | 0.87 | NPSR1 (0.36) | DRD2MCHR1UTS2RCCR3MEN1 | |
| SCHEMBL8665531 | 0.86 | CCR3 (0.41) | DRD2KDM5ACCR3 | |
| SCHEMBL8665590 | 0.85 | CTSB (0.34) | DRD2CCR3 | |
| SCHEMBL8485545 | 0.84 | NPSR1 (0.40) | MCHR1CCR3MEN1KMT2A | |
| SCHEMBL8717987 | 0.84 | CCR3 (0.44) | DRD2KDM5ACCR8CCR3MEN1 | |
| SCHEMBL8501239 | 0.83 | NPSR1 (0.33) | DRD2MCHR1UTS2RCCR3MEN1 | |
| SCHEMBL8484461 | 0.82 | NPSR1 (0.39) | MCHR1CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |