Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 7/20 | 0.35 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | CTSB | P07858 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665662 | 0.88 | HDAC2 (0.40) | CTSSCTSLCTSBMEN1KMT2A | |
| SCHEMBL8672057 | 0.84 | GRM5 (0.39) | GRM5CYP2C9CYP2C19MEN1ALDH1A1 | |
| SCHEMBL8666837 | 0.82 | HTT (0.43) | CTSSCTSLCTSBMEN1ALDH1A1 | |
| SCHEMBL8871034 | 0.78 | KMT2A (0.38) | CYP2C9CYP2C19MEN1ALDH1A1KMT2A | |
| SCHEMBL8666857 | 0.78 | KMT2A (0.38) | CYP2C9CYP2C19MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8666991 | 0.78 | KMT2A (0.37) | CYP2C9CYP2C19MEN1ALDH1A1KMT2A | |
| SCHEMBL8668534 | 0.76 | SMN1; SMN2 (0.46) | MEN1ALDH1A1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8685324 | 0.74 | L3MBTL1 (0.38) | CYP2C9MEN1KMT2ACYP3A4USP2 | |
| SCHEMBL8666219 | 0.73 | KMT2A (0.34) | CTSSCTSLCTSBCYP2C9MEN1 | |
| SCHEMBL8689402 | 0.72 | MEN1 (0.35) | CYP2C9CYP2C19MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |