Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665662 | 0.91 | HDAC2 (0.40) | CTSSCTSLCTSBSMN1; SMN2POLB | |
| SCHEMBL8666857 | 0.82 | KMT2A (0.38) | POLBRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8871034 | 0.82 | KMT2A (0.38) | POLBRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8665746 | 0.82 | ALDH1A1 (0.40) | HTTSMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL8666307 | 0.82 | GRM5 (0.38) | CTSSCTSLCTSBSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8666991 | 0.81 | KMT2A (0.37) | POLBRAB9AALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8683994 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2POLBALDH1A1HSD17B10 | |
| SCHEMBL8668534 | 0.78 | SMN1; SMN2 (0.46) | HTTSMN1; SMN2POLBRAB9AALDH1A1 | |
| SCHEMBL8685324 | 0.75 | L3MBTL1 (0.38) | POLBMEN1KMT2AKDM4E | |
| SCHEMBL8689402 | 0.75 | MEN1 (0.35) | HTTPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |