Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664750 | 0.87 | ALDH1A1 (0.53) | MAPTPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8665764 | 0.86 | MYC (0.47) | MAPTALDH1A1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL2493563 | 0.81 | TSHR (0.45) | MAPTALDH1A1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL80422 | 0.80 | TDP1 (0.49) | MAPTALDH1A1KMT2AKDM4ECYP1A2 | |
| SCHEMBL8078179 | 0.80 | TSHR (0.44) | MAPTPOLBALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8663910 | 0.80 | TSHR (0.44) | MAPTPOLBERN1ALDH1A1KMT2A | |
| SCHEMBL2492082 | 0.79 | TSHR (0.42) | MAPTALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL2497787 | 0.79 | EGFR (0.52) | MAPTALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL8668402 | 0.78 | RAB9A (0.48) | MAPTPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8664266 | 0.77 | MAPT (0.41) | MAPTPOLBALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |