Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | UBE2M | P61081 | 4/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676079 | 0.98 | CCKBR (0.35) | CCKBREPHX2UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL8663540 | 0.84 | BRD4 (0.31) | KMT2ADRD2DRD3 | |
| SCHEMBL8655308 | 0.83 | KCNQ3 (0.32) | — | |
| SCHEMBL8648884 | 0.83 | — | — | |
| SCHEMBL8655154 | 0.83 | HCRTR2 (0.33) | — | |
| SCHEMBL8482395 | 0.83 | MAPT (0.38) | KMT2AALDH1A1MEN1CCR3DRD2 | |
| SCHEMBL8650737 | 0.82 | POLB (0.32) | ALDH1A1 | |
| SCHEMBL8479118 | 0.82 | OPRK1 (0.32) | KMT2ADRD2DRD3 | |
| SCHEMBL8655139 | 0.82 | F10 (0.32) | — | |
| SCHEMBL8652603 | 0.81 | USP30 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |