Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665114 | 0.74 | PTGS2 (0.37) | PTGS2PTGS1PDPK1CACNB4CACNA1A | |
| SCHEMBL2460294 | 0.68 | RAPGEF4 (0.37) | RAPGEF4 | |
| SCHEMBL8719024 | 0.67 | LMNA (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2464163 | 0.66 | TRIM24 (0.42) | ALDH1A1 | |
| SCHEMBL7062997 | 0.65 | CA1 (0.45) | PTGS2PTGS1HTR6 | |
| SCHEMBL2461960 | 0.65 | DDR1 (0.35) | RAPGEF4 | |
| SCHEMBL11357896 | 0.64 | PCSK9 (0.50) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL29485475 | 0.63 | BAZ2B (0.33) | ALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8634800 | 0.62 | PCSK9 (0.44) | PTGS2PTGS1ALDH1A1MAPTHTR6 | |
| SCHEMBL22032554 | 0.62 | KDM4E (0.42) | KDM4EMEN1NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739155-A | Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 1998-04-14 | — | — | US | disclosed |