Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616494 | 0.80 | CA12 (0.41) | LMNAHPGDSMN1; SMN2TNKSTNKS2 | |
| SCHEMBL152089 | 0.80 | CA12 (0.41) | LMNAHPGDSMN1; SMN2TNKSTNKS2 | |
| SCHEMBL8665808 | 0.79 | CYP1A2 (0.45) | HPGDTNKSTNKS2L3MBTL1 | |
| SCHEMBL491149 | 0.77 | CYP1A1 (0.45) | LMNASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL8665239 | 0.76 | MAPT (0.47) | IDO1LMNAHPGDSMN1; SMN2ACACA | |
| SCHEMBL8665295 | 0.76 | CYP2A6 (0.45) | LMNAMAPT | |
| SCHEMBL11595679 | 0.75 | KMT2A (0.37) | LMNAHPGDSMN1; SMN2TNKSTNKS2 | |
| SCHEMBL5841127 | 0.74 | ALDH1A1 (0.40) | LMNAHPGDSMN1; SMN2TNKSTNKS2 | |
| SCHEMBL8666981 | 0.71 | MAPT (0.39) | LMNAHPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL419307 | 0.71 | IDO1 (0.73) | IDO1EP300KAT8LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |