Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148165 | 0.81 | CLK4 (0.50) | EGFRIGF1RALDH1A1LMNAHTT | |
| SCHEMBL2450873 | 0.81 | CLK4 (0.50) | EGFRIGF1RALDH1A1LMNAHTT | |
| SCHEMBL9369713 | 0.79 | KMT2A (0.48) | FLT4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31343882 | 0.78 | BACE1 (0.65) | BACE1PKMEGFRFABP1FABP6 | |
| SCHEMBL9369388 | 0.77 | CLK1 (0.38) | KDM4CHTTSMN1; SMN2KDM4EMAPT | |
| SCHEMBL3448086 | 0.76 | AOC1 (0.38) | KDM4CALDH1A1CYP1A2NOS2HSD17B10 | |
| SCHEMBL8562887 | 0.75 | BACE1 (0.52) | BACE1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2572082 | 0.75 | HTT (0.50) | PKMEGFRIGF1RALDH1A1CYP1A2 | |
| SCHEMBL19432620 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6MAPK1CYP2C19 | |
| SCHEMBL783719 | 0.74 | KDM4C (0.72) | EGFRKDM4CALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10471139-B2 | Toll-like receptor agonists | THE UNIVERSITY OF KANSAS (US) | 2019-11-12 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS | 2016-06-16 | — | — | US | disclosed |
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |
| US-5723468-A | COGNITION ACTIVATORS FOR MEMOY LOSS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5571819-A | Imidazopyridines as muscarinic agents | WYETH | 1996-11-05 | — | — | US | disclosed |
| EP-0399653-B1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | WELLCOME FOUND (GB) | 1994-10-19 | — | — | EP | disclosed |
| US-5240937-A | Treatment of epilepsy | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0399653-A1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166681-A1 | TOLL-LIKE RECEPTOR AGONISTS | TLR1, TLR7, TLR8 | BACE1 2969/4885PKM 1205/4885EGFR 1923/4885 |
| US-10471139-B2 | Toll-like receptor agonists | TLR1, TLR7, TLR8 | BACE1 2969/4885PKM 1205/4885EGFR 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.