Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Chloromethyl)Benzene SCHEMBL700512 | 0.90 | OPRM1 (0.53) | MAPTKCNH2DRD2OPRM1DRD3 | |
| (Chloromethyl)Benzene SCHEMBL17022934 | 0.84 | KCNH2 (0.59) | KCNH2DRD2OPRM1DRD3OPRD1 | |
| SCHEMBL10990959 | 0.82 | MAPT (0.58) | MAPTKCNH2 | |
| (Chloromethyl)Benzene SCHEMBL10767165 | 0.82 | KCNH2 (0.62) | KCNH2DRD2OPRM1DRD3OPRD1 | |
| SCHEMBL4870098 | 0.81 | EGFR (0.49) | MAPTKCNH2 | |
| Hydrochloric Acid SCHEMBL3373755 | 0.79 | EGFR (0.47) | MAPTKCNH2 | |
| SCHEMBL1006989 | 0.76 | CA2 (0.54) | THRATHRB | |
| (Chloromethyl)Benzene SCHEMBL7216279 | 0.76 | DRD3 (0.50) | KCNH2DRD2OPRM1DRD3OPRD1 | |
| SCHEMBL1445861 | 0.74 | ESR1 (0.59) | KCNH2THRATHRB | |
| Chloromethane SCHEMBL516316 | 0.74 | CA12 (0.42) | MAPTKCNH2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630884-B1 | Method and composition providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants | LUMIGEN INC (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5650099-A | ARYL PHOSPHONIUM OR PHOSPHONIUM/AMMONIUM SURFACTANTS | LUMIGEN, INC. (US) | 1997-07-22 | — | — | US | disclosed |
| US-5484556-A | AMMONIUM OR PHOSPHONIUM CATIONIC SURFACTANT | LUMIGEN, INC. (US) | 1996-01-16 | — | — | US | disclosed |
| US-5451347-A | 1,2-dioxetans with ammonium or phosphonium compounds | LUMIGEN, INC. (US) | 1995-09-19 | — | — | US | disclosed |