(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL700512

CCCCN(CCCC)CCCC.ClCc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.53
DRD3 P35462 4/20 0.53
DRD2 P14416 3/20 0.53
OPRD1 P41143 3/20 0.53
OPRK1 P41145 3/20 0.53
KCNH2 Q12809 6/20 0.51
CHRM2 P08172 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
CHRM1 P11229 1/20 0.50
DRD1 P21728 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
ADRA1A P35348 1/20 0.50
SLC6A3 Q01959 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
BCHE P06276 1/20 0.46
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL17022934 0.94 KCNH2 (0.59) OPRM1DRD3DRD2OPRD1OPRK1
(Chloromethyl)Benzene SCHEMBL10767165 0.92 KCNH2 (0.62) OPRM1DRD3DRD2OPRD1OPRK1
SCHEMBL8666908 0.90 MAPT (0.52) OPRM1DRD3DRD2OPRD1OPRK1
(Chloromethyl)Benzene SCHEMBL7216279 0.88 DRD3 (0.50) OPRM1DRD3DRD2OPRD1OPRK1
(Chloromethyl)Benzene SCHEMBL27477517 0.85 SIGMAR1 (0.50) KCNH2MEN1KMT2A
SCHEMBL6947636 0.82 OPRM1 (0.73) OPRM1DRD3DRD2OPRD1OPRK1
SCHEMBL5879246 0.82 OPRM1 (0.73) OPRM1DRD3DRD2OPRD1OPRK1
SCHEMBL12540441 0.82 OPRM1 (0.74) OPRM1DRD3DRD2OPRD1OPRK1
Benzyl Bromide SCHEMBL457700 0.82 TRPA1 (0.58) OPRM1DRD3DRD2OPRD1OPRK1
SCHEMBL9720308 0.82 MAPT (0.58) OPRM1DRD3DRD2OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117258767-B Novel psychoactive substance adsorbent and application thereof 西南政法大学 2026-05-19 CN claimed
CN-119555859-A High-sensitivity high-flux identification method for saccharide compounds based on chlorine enhanced ionization 北京大学 2025-03-04 CN claimed
CN-119431161-A Synthesis method of mebeverine hydrochloride 河北广祥制药有限公司 2025-02-14 CN claimed
CN-119281376-A Molecular sieve catalyst, preparation method thereof and application thereof in preparation of substituted aromatic hydrocarbon compounds 浙江新和成股份有限公司 2025-01-10 CN claimed
CN-118791342-A Method for optimizing TATB performance based on curing effect 西南科技大学 2024-10-18 CN claimed
WO-2023159094-A2 PROCESS OF MAKING 3α-HYDROXY-3β-METHOXYMETHYL-21-(1'- IMIDAZOLYL)-5α-PREGNAN-20-ONE PRAXIS PRECISION MEDICINES, INC. (US) 2023-08-24 WO claimed
US-11719695-B2 Immunoassay method to prevent inhibition of antigen-antibody binding interactions in mucosal fluids NH FOODS LTD (JP) 2023-08-08 US claimed
US-20190127311-A1 C-HALOGEN BOND FORMATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2019-05-02 US claimed
US-10196341-B2 C-halogen bond formation THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2019-02-05 US claimed
US-20140249329-A1 C-HALOGEN BOND FORMATION THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-09-04 US claimed
EP-1841739-B1 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL] PIPERIDINE OR SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LTD (IN) 2013-02-20 EP claimed
US-8124783-B2 Process for producing 1-benzyl-4-[5,6-dimethoxy-1-indanon-2-yl)methyl] piperidine or its salt thereof via novel intermediate JUBILANT ORGANOSYS LIMITED (IN) 2012-02-28 US claimed
WO-2011030213-A8 IMPROVED PROCESS FOR THE PREPARATION OF 7-(4-BROMOBUTOXY) 3,4-DIHYDROCARBOSTYRIL, A PRECURSOR OF ARIPIPRAZOLE JUBILANT LIFE SCIENCES LIMITED (IN) 2011-05-19 WO claimed
WO-2011030213-A1 IMPROVED PROCESS FOR THE PREPARATION OF 7.(4-BROMOBUTOXY) 3,4-DIHYDROCARBOSTYRIL, A PRECURSOR OF ARIPIPRAZOLE JUBILANT ORGANOSYS LIMITED (IN) 2011-03-17 WO claimed
US-20090137812-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LIMITED (IN) 2009-05-28 US claimed
EP-1841739-A4 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LTD (IN) 2008-10-01 EP claimed
US-7390927-B2 Process for preparing 3-aminophenylacetylenes FUJILFILM CORPORATION (JP) 2008-06-24 US claimed
EP-1841739-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE Jubilant Organosys Limited (IN) 2007-10-10 EP claimed
US-20060224016-A1 Process for preparing 3-aminophenylacetylenes FUJI PHOTO FILM CO., LTD. 2006-10-05 US claimed
WO-2006070396-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON­2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LIMITED (IN) 2006-07-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137812-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE TET2, DHPS, AZI2 OPRM1 1184/4885DRD3 1436/4885DRD2 599/4885
US-20190127311-A1 C-HALOGEN BOND FORMATION CBR3, FOS, CBR1 OPRM1 3199/4885DRD3 246/4885DRD2 969/4885
US-20060224016-A1 Process for preparing 3-aminophenylacetylenes NAT1, NAT10, KAT7 OPRM1 2808/4885DRD3 1429/4885DRD2 1671/4885
US-20140249329-A1 C-HALOGEN BOND FORMATION CBR3, FOS, CBR1 OPRM1 3199/4885DRD3 246/4885DRD2 969/4885
US-10196341-B2 C-halogen bond formation CBR3, FOS, CBR1 OPRM1 3199/4885DRD3 246/4885DRD2 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.