Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 6/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524381 | 0.96 | CCR3 (0.42) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8665515 | 0.90 | CCR3 (0.41) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8665525 | 0.90 | CCR3 (0.40) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8665477 | 0.89 | DRD2 (0.37) | CCR3DRD2 | |
| SCHEMBL8717983 | 0.86 | CCR3 (0.43) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8712537 | 0.85 | CCR3 (0.43) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8717870 | 0.85 | NPSR1 (0.38) | CCR3DRD2MEN1KMT2ASLC6A12 | |
| SCHEMBL8665880 | 0.81 | UTS2R (0.39) | DRD2 | |
| SCHEMBL8666092 | 0.80 | UTS2R (0.39) | DRD2 | |
| SCHEMBL8664869 | 0.78 | SMPD3 (0.38) | KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |