Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | DRD4 | P21917 | 7/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717870 | 0.95 | NPSR1 (0.38) | DRD2DRD4NPSR1MCHR1SCN1A | |
| SCHEMBL8666998 | 0.89 | CCR3 (0.40) | DRD2CCR3 | |
| SCHEMBL8665880 | 0.89 | UTS2R (0.39) | DRD2DRD4UTS2RNPSR1MCHR1 | |
| SCHEMBL8666092 | 0.89 | UTS2R (0.39) | DRD2DRD4UTS2RNPSR1MCHR1 | |
| SCHEMBL8524381 | 0.85 | CCR3 (0.42) | DRD2NPSR1CCR3 | |
| SCHEMBL8485533 | 0.84 | NPSR1 (0.42) | DRD2UTS2RNPSR1MCHR1SCN1A | |
| SCHEMBL8484454 | 0.84 | NPSR1 (0.42) | DRD2UTS2RNPSR1MCHR1SCN1A | |
| SCHEMBL8501233 | 0.83 | NPSR1 (0.36) | DRD2DRD4UTS2RNPSR1SCN9A | |
| SCHEMBL8501048 | 0.82 | NPSR1 (0.35) | UTS2RNPSR1SCN9A | |
| SCHEMBL8669685 | 0.80 | NPSR1 (0.42) | DRD2DRD4UTS2RNPSR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |