Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351783 | 0.85 | RAD52 (0.45) | RAD52KMT2ATDP2NSD2CXCR2 | |
| SCHEMBL7350556 | 0.74 | MAPKAPK2 (0.43) | RAD52KMT2ATDP2NSD2LMNA | |
| SCHEMBL19956891 | 0.74 | KMT2A (0.49) | RAD52KMT2ATDP2NSD2ADRA2A | |
| SCHEMBL4023982 | 0.73 | POLB (0.55) | RAD52KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL7346763 | 0.71 | TDO2 (0.50) | RAD52KMT2ATDP2NSD2ADRA2A | |
| SCHEMBL10082731 | 0.71 | CXCR2 (0.54) | KMT2AADAMTS5CXCR2ITGB1ITGA4 | |
| SCHEMBL2771874 | 0.71 | POLB (0.46) | RAD52KMT2ATDP2NSD2KDM4E | |
| SCHEMBL7349452 | 0.71 | PLK1 (0.55) | RAD52KMT2ATDP2NSD2 | |
| SCHEMBL15061601 | 0.68 | LMNA (0.54) | KMT2ANOTUMSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6987237 | 0.68 | KMT2A (0.42) | RAD52KMT2ATDP2NSD2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729457-B1 | DIAMINOCYCLOBUTENE-3,4-DIONES AS SMOOTH MUSCLE RELAXANTS | AMERICAN HOME PROD (US) | 1998-12-23 | — | — | EP | claimed |