Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482587 | 0.96 | CCR3 (0.43) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8665520 | 0.85 | CCR3 (0.42) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8665531 | 0.84 | CCR3 (0.41) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8717987 | 0.81 | CCR3 (0.44) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8712541 | 0.80 | CCR3 (0.44) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8653118 | 0.75 | CCR3 (0.43) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8667924 | 0.73 | CCR3 (0.48) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8665883 | 0.73 | NPSR1 (0.37) | CCR3DRD2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8663914 | 0.73 | CCR3 (0.47) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8664874 | 0.73 | DRD2 (0.33) | CCR3KDM5ADRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |