Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MYOC | Q99972 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665352 | 0.88 | KMT2A (0.53) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL8664451 | 0.86 | MEN1 (0.62) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL9004670 | 0.81 | MAPT (0.55) | KMT2AMEN1MAOBMAPTNPC1 | |
| SCHEMBL9004631 | 0.81 | SMN1; SMN2 (0.51) | KMT2AMEN1MAOBMAPTNPC1 | |
| SCHEMBL9004705 | 0.81 | MAOB (0.54) | KMT2AMEN1MAOAMAOBMAPT | |
| SCHEMBL9227706 | 0.81 | MAPT (0.51) | KMT2AMEN1MAOBMAPTNPC1 | |
| SCHEMBL9004678 | 0.81 | SMN1; SMN2 (0.51) | KMT2AMEN1MAOBMAPTNPC1 | |
| SCHEMBL9004758 | 0.79 | SENP6 (0.67) | KMT2AMEN1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL8667033 | 0.79 | KMT2A (0.51) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL9004724 | 0.78 | EPHX2 (0.57) | KMT2AMEN1MAOBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |