Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004741 | 0.79 | MAPT (0.53) | KMT2AMEN1NPC1CASP3TP53 | |
| SCHEMBL8667290 | 0.79 | KMT2A (0.56) | KMT2AMEN1NPC1CASP3ALDH1A1 | |
| SCHEMBL9004654 | 0.78 | KMT2A (0.51) | KMT2AMEN1NPC1CASP3ALDH1A1 | |
| SCHEMBL9004618 | 0.78 | KMT2A (0.63) | KMT2AMEN1NPC1CASP3ALDH1A1 | |
| SCHEMBL9232385 | 0.78 | SENP6 (0.51) | KMT2AMEN1NPC1CASP3ALDH1A1 | |
| SCHEMBL9004650 | 0.78 | MAPT (0.51) | KMT2AMEN1NPC1CASP3TP53 | |
| SCHEMBL9004668 | 0.78 | RAB9A (0.57) | KMT2AMEN1NPC1CASP3ALDH1A1 | |
| SCHEMBL11332310 | 0.78 | KMT2A (0.73) | KMT2AMEN1NPC1TP53ALDH1A1 | |
| SCHEMBL8664451 | 0.76 | MEN1 (0.62) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL9231193 | 0.75 | SMN1; SMN2 (0.47) | KMT2AMEN1CASP3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |