Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | DDX3X | O00571 | 2/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665352 | 0.87 | KMT2A (0.53) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL8667290 | 0.86 | KMT2A (0.56) | MEN1KMT2AMAPTPOLBMAPK1 | |
| SCHEMBL8667830 | 0.80 | SENP6 (0.61) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL9004624 | 0.80 | RAB9A (0.50) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL9004754 | 0.80 | STING1 (0.50) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL9004666 | 0.80 | KMT2A (0.52) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL9227877 | 0.80 | DDX3X (0.58) | MEN1KMT2AMAPTHTTDDX3X | |
| Water SCHEMBL9571731 | 0.79 | KMT2A (0.51) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL1047211 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL6129390 | 0.77 | MEN1 (0.90) | MEN1KMT2AMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |