Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667290 | 0.88 | KMT2A (0.56) | KMT2AMEN1MAPTKDM4ECCR6 | |
| SCHEMBL8664451 | 0.87 | MEN1 (0.62) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL8667830 | 0.82 | SENP6 (0.61) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL9004617 | 0.81 | TRPV1 (0.48) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| SCHEMBL9004669 | 0.81 | TRPV1 (0.48) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| SCHEMBL8664300 | 0.80 | SMN1; SMN2 (0.50) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL9004630 | 0.77 | SENP6 (0.55) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL9004632 | 0.77 | SENP6 (0.55) | KMT2AMEN1MAPTLMNAPOLB | |
| SCHEMBL9004644 | 0.75 | KMT2A (0.50) | KMT2AMEN1MAPTKDM4ELMNA | |
| Water SCHEMBL9038240 | 0.74 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |