Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HCN1 | O60741 | 1/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026753 | 0.81 | LMNA (0.47) | LMNAP2RX7MEN1KMT2AGAA | |
| SCHEMBL1756726 | 0.78 | LMNA (0.63) | LMNAP2RX7MEN1KMT2AGAA | |
| SCHEMBL13067094 | 0.72 | LMNA (0.71) | LMNAP2RX7MEN1KMT2AGAA | |
| SCHEMBL13952095 | 0.71 | ALOX5 (0.82) | ALOX5TERTALDH1A1 | |
| SCHEMBL3677100 | 0.71 | ALOX5 (0.64) | ALOX5TERTEGLN2EGLN1ALDH1A1 | |
| SCHEMBL29387023 | 0.71 | ALOX5 (0.64) | ALOX5TERTEGLN2EGLN1ALDH1A1 | |
| SCHEMBL11188791 | 0.70 | TSHR (0.50) | MEN1KMT2A | |
| SCHEMBL15822231 | 0.70 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL26936095 | 0.70 | ALOX5 (0.79) | ALOX5TERTMEN1KMT2AALDH1A1 | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL10570084 | 0.69 | SELL (0.61) | ALOX5TERTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854250-A | N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same | GYOGYSZERKUTATO INTEZET KFT (HU) | 1998-12-29 | — | — | US | disclosed |
| US-5705529-A | ANTIISCHEMIC AGENTS, ANTIINFLAMMATORY AGENTS, AGING RESISTANCE, ATHERIOSCLEROSIS, NERVOUS SYSTEM DISORDERS | GYOGYSZERKUTATO INTEZET KFT (HK) | 1998-01-06 | — | — | US | disclosed |
| EP-0576941-B1 | N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same | NISSHIN FLOUR MILLING CO (JP) | 1997-09-03 | — | — | EP | disclosed |
| EP-0576941-A1 | N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-01-05 | — | — | EP | disclosed |