SCHEMBL866755

SCHEMBL866755

N#CCOC(=O)c1cc([N+](=O)[O-])ccc1O[C]=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ KMT2A Q03164 6/20 0.39
▸ MEN1 O00255 5/20 0.39
▸ THRB P10828 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ HTT P42858 3/20 0.38
▸ TP53 P04637 1/20 0.38
▸ CTSB P07858 1/20 0.38
▸ MAPT P10636 5/20 0.38
▸ LMNA P02545 3/20 0.38
▸ PKM P14618 1/20 0.36
▸ GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14414728 0.82 RAB9A (0.50) ALDH1A1SMN1; SMN2THRBTDP1HTT
SCHEMBL8741183 0.76 ALOX5 (0.53) ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E
SCHEMBL10578797 0.75 KMT2A (0.56) ALDH1A1SMN1; SMN2KMT2AMEN1THRB
SCHEMBL8758376 0.72 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2KMT2AMEN1THRB
SCHEMBL14414729 0.72 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E
SCHEMBL13461771 0.71 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E
SCHEMBL13461764 0.71 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1KDM4EHTT
SCHEMBL4941803 0.69 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2KMT2AMEN1TDP1
SCHEMBL12236634 0.69 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E
SCHEMBL31384439 0.69 CTSD (0.50) ALDH1A1SMN1; SMN2KMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465938-B2 Method for producing complex of biotin-labeled Cypridina (Cypridina noctiluca) luciferase with streptoavidin and method for stabilizing the same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLGY (JP) 2013-06-18 — — US disclosed
US-20120077205-A1 METHOD FOR PRODUCING COMPLEX OF BIOTIN-LABELED CYPRIDINA (CYPRIDINA NOCTILUCA) LUCIFERASE WITH STREPTOAVIDIN AND METHOD FOR STABILIZING THE SAME OHMIYA YOSHIHIRO (JP) 2012-03-29 — — US disclosed
US-20080108097-A1 METHOD FOR PRODUCING COMPLEX OF BIOTIN-LABELED CYPRIDINA (CYPRIDINA NOCTILUCA) LUCIFERASE WITH STREPTOAVIDIN AND METHOD FOR STABILIZING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2008-05-08 — — US disclosed
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