SCHEMBL8667576

SCHEMBL8667576

CC(=O)OCc1ccccc1-n1c(Cl)nn(C)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
CYP1A2 P05177 3/20 0.38
CYP2C19 P33261 3/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.37
SETDB1 Q15047 1/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
IDH1 O75874 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8664792 0.85 SETDB1 (0.42) ALDH1A1SMN1; SMN2CYP1A2CYP2C19CYP3A4
SCHEMBL8663188 0.84 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2CYP1A2CYP2C19CYP3A4
SCHEMBL8155272 0.79 NPC1 (0.34) ALDH1A1SMN1; SMN2MEN1KMT2ASETDB1
SCHEMBL8590523 0.73 KDM4E (0.47) ALDH1A1CYP1A2MEN1KMT2AGAA
SCHEMBL21848041 0.72 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CYP1A2CYP2C19CYP3A4
SCHEMBL8481561 0.72 MYC (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL8593864 0.71 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2KMT2ANPC1L3MBTL1
SCHEMBL5255523 0.70 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2CYP1A2CYP2C19CYP3A4
SCHEMBL2659085 0.69 RAB9A (0.57) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL27811798 0.69 NCF1 (0.51) ALDH1A1SMN1; SMN2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874831-A1 PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-11-04 EP disclosed
WO-1997019935-A1 PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-06-05 WO disclosed