Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663188 | 0.89 | ALDH1A1 (0.42) | SETDB1SMN1; SMN2GALR3CYP1A2CYP3A4 | |
| SCHEMBL8664656 | 0.88 | SETDB1 (0.40) | SETDB1SMN1; SMN2GALR3CYP1A2CYP3A4 | |
| SCHEMBL8667576 | 0.85 | ALDH1A1 (0.39) | SETDB1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8670561 | 0.81 | DDR1 (0.35) | SETDB1SMN1; SMN2GALR3CYP1A2CYP3A4 | |
| SCHEMBL13034130 | 0.71 | GAA (0.49) | SMN1; SMN2CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL27752252 | 0.70 | MRGPRX4 (0.47) | SMN1; SMN2CYP3A4L3MBTL1LMNAGAA | |
| SCHEMBL8664609 | 0.69 | SETDB1 (0.37) | SETDB1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11888397 | 0.68 | GAA (0.64) | SMN1; SMN2GALR3CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8675983 | 0.68 | SETDB1 (0.38) | SETDB1SMN1; SMN2HTTL3MBTL1LMNA | |
| SCHEMBL13034132 | 0.67 | ADRB2 (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874831-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019935-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |