SCHEMBL8667684

SCHEMBL8667684

CC(C)N(O)Cc1ccc(C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
MEP1B Q16820 1/20 0.51
ALDH2 P05091 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
TAS2R14 Q9NYV8 9/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 1/20 0.46
HSP90AA1 P07900 1/20 0.46
PSEN1 P49768 1/20 0.46
PSEN2 P49810 1/20 0.46
APH1B Q8WW43 1/20 0.46
NCSTN Q92542 1/20 0.46
APH1A Q96BI3 1/20 0.46
PSENEN Q9NZ42 1/20 0.46
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8781908 0.81 LOXL2 (0.54) ALDH1A1HDAC1HDAC8HDAC6HSP90AA1
SCHEMBL8781885 0.79 ALDH1A1 (0.57) ALDH1A1MEP1BALDH2TAS2R14KMT2A
SCHEMBL3239026 0.78 ALDH1A1 (0.56) ALDH1A1MEP1BALDH2TAS2R14KMT2A
SCHEMBL20333453 0.78 KMT2A (0.53) ALDH1A1KMT2AMEN1TSHR
SCHEMBL4289838 0.77 HDAC8 (0.66) ALDH1A1MEP1BALDH2HDAC8HDAC6
SCHEMBL65825 0.76 ALDH1A1 (0.59) ALDH1A1MEP1BALDH2TAS2R14KMT2A
SCHEMBL8781906 0.76 CA12 (0.38) HDAC1HDAC8HDAC6KMT2AMEN1
Hydrochloric Acid SCHEMBL6297059 0.76 HDAC8 (0.64) ALDH1A1MEP1BALDH2HDAC8HDAC6
SCHEMBL13227060 0.75 KMT2A (0.51) ALDH1A1MEP1BHDAC1HDAC8HDAC6
SCHEMBL9681275 0.75 ALDH1A1 (0.46) ALDH1A1PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0884640-A1 Processing of photographic elements using N,N-dialkylhydroxylamine antioxidants in photographic color developers EASTMAN KODAK COMPANY (US) 1998-12-16 EP claimed
EP-0686874-B1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK CO (US) 1997-12-17 EP claimed
US-5660974-A EXPOSING, DEVELOPING EASTMAN KODAK COMPANY (US) 1997-08-26 US claimed
EP-0759190-A1 N-ALKYLHYDROXYLAMINE DERIVATIVES AND THEIR USE AS ANTIOXIDANTS IN PHOTOGRAPHIC COLOR DEVELOPERS AND PROCESSING METHODS EASTMAN KODAK COMPANY (US) 1997-02-26 EP claimed
WO-1996028761-A1 N-ALKYLHYDROXYLAMINE DERIVATIVES AND THEIR USE AS ANTIOXIDANTS IN PHOTOGRAPHIC COLOR DEVELOPERS AND PROCESSING METHODS EASTMAN KODAK COMPANY (US) 1996-09-19 WO claimed
EP-0686874-A1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK COMPANY (US) 1995-12-13 EP claimed
EP-0884640-A1 Processing of photographic elements using N,N-dialkylhydroxylamine antioxidants in photographic color developers EASTMAN KODAK COMPANY (US) 1998-12-16 EP disclosed
EP-0686874-B1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK CO (US) 1997-12-17 EP disclosed
US-5660974-A EXPOSING, DEVELOPING EASTMAN KODAK COMPANY (US) 1997-08-26 US disclosed
EP-0759190-A1 N-ALKYLHYDROXYLAMINE DERIVATIVES AND THEIR USE AS ANTIOXIDANTS IN PHOTOGRAPHIC COLOR DEVELOPERS AND PROCESSING METHODS EASTMAN KODAK COMPANY (US) 1997-02-26 EP disclosed
WO-1996028761-A1 N-ALKYLHYDROXYLAMINE DERIVATIVES AND THEIR USE AS ANTIOXIDANTS IN PHOTOGRAPHIC COLOR DEVELOPERS AND PROCESSING METHODS EASTMAN KODAK COMPANY (US) 1996-09-19 WO disclosed
EP-0686874-A1 Color developer containing hydroxylamine antioxidants EASTMAN KODAK COMPANY (US) 1995-12-13 EP disclosed