SCHEMBL8667754

SCHEMBL8667754

CCc1cccc2c1C(=O)c1ccccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.48
ALDH1A1 P00352 5/20 0.48
LMNA P02545 4/20 0.48
MAPK1 P28482 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAOA P21397 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HTT P42858 2/20 0.48
CES2 O00748 1/20 0.48
APAF1 O14727 1/20 0.48
TERT O14746 1/20 0.48
PLIN1 O60240 1/20 0.48
TDP2 O95551 1/20 0.48
S1PR4 O95977 1/20 0.48
PLA2G1B P04054 1/20 0.48
BCHE P06276 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83136 0.92 ADORA2A (0.53) MAPTALDH1A1LMNAMAPK1MEN1
SCHEMBL1480067 0.90 MAPT (0.47) MAPTALDH1A1LMNAMAPK1MEN1
SCHEMBL10883505 0.89 MAOA (0.48) MAPTALDH1A1LMNAMAPK1NPC1
SCHEMBL10886395 0.86 ELANE (0.45) MAPTALDH1A1LMNAMAPK1MEN1
Boric Acid SCHEMBL29849803 0.85 MAPT (0.47) MAPTALDH1A1LMNAMAPK1MEN1
SCHEMBL11550615 0.85 PDK2 (0.47) MAPTALDH1A1LMNAMAPK1NPC1
SCHEMBL10063730 0.85 MAPT (0.50) MAPTALDH1A1LMNAMAPK1MEN1
SCHEMBL10783896 0.85 PDK2 (0.47) MAPTALDH1A1LMNAMAPK1NPC1
SCHEMBL7006710 0.85 PDK2 (0.47) MAPTALDH1A1LMNAMAPK1NPC1
SCHEMBL8671230 0.83 ELANE (0.48) MAPTALDH1A1LMNAMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115528215-A Secondary battery positive electrode material pre-ionization reagent and preparation method and application thereof 深圳珈钠能源科技有限公司 2022-12-27 CN claimed
CN-113248441-A Dual-functional ionic liquid, preparation method thereof and application thereof in catalytic synthesis of bisphenol compound 大连理工大学 2021-08-13 CN claimed
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-11-23 US disclosed
EP-4255151-A2 SPIRO[FLUORENE-9,9'-(THIO)XANTHENE] COMPOUNDS Merck Patent GmbH (DE) 2023-10-04 EP disclosed
EP-4113643-B1 SPIRO[FLUORENE-9,9'-(THIO)XANTHENE] COMPOUNDS MERCK PATENT GMBH (DE) 2023-08-09 EP disclosed
EP-3523834-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-01-25 EP disclosed
EP-4113643-A1 ELECTRONIC DEVICE Merck Patent GmbH (DE) 2023-01-04 EP disclosed
CN-115528215-A Secondary battery positive electrode material pre-ionization reagent and preparation method and application thereof 深圳珈钠能源科技有限公司 2022-12-27 CN disclosed
CN-113248441-A Dual-functional ionic liquid, preparation method thereof and application thereof in catalytic synthesis of bisphenol compound 大连理工大学 2021-08-13 CN disclosed
US-10308607-B2 Fucosidase inhibitors HORIZON ORPHAN LLC (US) 2019-06-04 US disclosed
WO-2017019925-A1 FUCOSIDASE INHIBITORS RAPTOR PHARMACEUTICALS INC. (US) 2017-02-02 WO disclosed
US-20110166141-A1 CATHEPSIN S INHIBITORS DCB-USA, LLC (US) 2011-07-07 US disclosed
EP-0886182-A1 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230373941-A1 COMPOUNDS FOR ELECTRONIC DEVICES CYP2E1, GPX1, ERCC1 MAPT 2951/4885ALDH1A1 115/4885LMNA 2835/4885
US-10308607-B2 Fucosidase inhibitors FUCA1, FUCA2, ENGASE MAPT 3789/4885ALDH1A1 588/4885LMNA 3460/4885
US-20110166141-A1 CATHEPSIN S INHIBITORS CTSS, CTSV, CTSB MAPT 3934/4885ALDH1A1 2734/4885LMNA 4130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.