Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 10/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640125 | 0.85 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL30561524 | 0.85 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL27744229 | 0.84 | PNMT (0.48) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL14878929 | 0.78 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL7764313 | 0.77 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1950952 | 0.77 | DRD2 (0.51) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1953206 | 0.77 | DRD2 (0.59) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL12004879 | 0.77 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL29507804 | 0.77 | DRD2 (0.59) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL29370265 | 0.76 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |