Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665495 | 0.89 | CCR2 (0.35) | NPSR1GAA | |
| SCHEMBL8717987 | 0.87 | CCR3 (0.44) | CCR3KDM4EMAPTKDM5AHTT | |
| SCHEMBL8482402 | 0.87 | CCR3 (0.35) | CCR3L3MBTL1NPSR1SCN1ASCN2A | |
| SCHEMBL8665520 | 0.86 | CCR3 (0.42) | CCR3L3MBTL1NPSR1KDM4EKDM5A | |
| SCHEMBL8712541 | 0.85 | CCR3 (0.44) | CCR3L3MBTL1NPSR1KDM4EMAPT | |
| SCHEMBL8665531 | 0.84 | CCR3 (0.41) | CCR3L3MBTL1NPSR1KDM4EKDM5A | |
| SCHEMBL8668018 | 0.82 | MAPT (0.39) | CCR3L3MBTL1NPSR1SCN1ASCN2A | |
| SCHEMBL8577131 | 0.79 | GAA (0.34) | L3MBTL1NPSR1TSHRALDH1A1GAA | |
| SCHEMBL8574668 | 0.79 | GAA (0.36) | L3MBTL1NPSR1TSHRALDH1A1GAA | |
| SCHEMBL8653118 | 0.77 | CCR3 (0.43) | CCR3L3MBTL1NPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | claimed |