Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668024 | 0.89 | CCR3 (0.35) | GAANPSR1 | |
| SCHEMBL8485545 | 0.85 | NPSR1 (0.40) | GAANPSR1 | |
| SCHEMBL8665883 | 0.84 | NPSR1 (0.37) | CCR2NPSR1 | |
| SCHEMBL8501239 | 0.84 | NPSR1 (0.33) | GAANPSR1 | |
| SCHEMBL8484461 | 0.83 | NPSR1 (0.39) | GAANPSR1 | |
| SCHEMBL8666099 | 0.82 | NPSR1 (0.36) | CCR2NPSR1 | |
| SCHEMBL8501052 | 0.82 | NPSR1 (0.33) | GAANPSR1 | |
| SCHEMBL8501003 | 0.79 | CTSL (0.36) | SCN9A | |
| SCHEMBL8665488 | 0.78 | CCR2 (0.37) | CCR2KCNH2CCR5 | |
| SCHEMBL8578880 | 0.77 | TRPV1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | claimed |