Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917219 | 0.83 | CA1 (0.40) | EPAS1ALDH1A1MAPTERN1 | |
| SCHEMBL4608215 | 0.83 | EPAS1 (0.45) | EPAS1ALDH1A1ERN1 | |
| SCHEMBL26425416 | 0.82 | NFE2L2 (0.47) | EPAS1 | |
| SCHEMBL1201009 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MAPTERN1PTGDR2 | |
| SCHEMBL24795607 | 0.80 | ERN1 (0.38) | EPAS1ALDH1A1MAPTERN1PTGDR2 | |
| SCHEMBL29365458 | 0.80 | CA1 (0.45) | EPAS1ALDH1A1MAPT | |
| SCHEMBL22712463 | 0.80 | CA1 (0.45) | EPAS1ALDH1A1MAPT | |
| SCHEMBL3004721 | 0.80 | ALDH1A1 (0.48) | EPAS1ALDH1A1MAPTERN1 | |
| SCHEMBL10020233 | 0.80 | ALDH1A1 (0.49) | EPAS1ALDH1A1MAPTERN1 | |
| SCHEMBL29398687 | 0.80 | ALDH1A1 (0.48) | EPAS1ALDH1A1MAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269075-B | Efficient synthesis method of 2, 3-indanones | 西北工业大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-111269075-A | Efficient synthesis method of 2, 3-indanones | 西北工业大学 | 2020-06-12 | — | — | CN | disclosed |
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-9085567-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085567-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2012145737-A1 | FATTY ACID AMIDE HYDROLASE INHIBITORS FOR TREATING | ALLERGAN, INC. (US) | 2012-10-26 | — | — | WO | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2012024559-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | EPAS1 507/4885ALDH1A1 2036/4885MAPT 4843/4885 |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | FAAH, FAAH2, FAH | EPAS1 503/4885ALDH1A1 95/4885MAPT 3485/4885 |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | EPAS1 462/4885ALDH1A1 2310/4885MAPT 4765/4885 |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | EPAS1 507/4885ALDH1A1 2036/4885MAPT 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.