Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592729 | 0.73 | ALOX5 (0.31) | NPC1RAB9A | |
| SCHEMBL8668167 | 0.70 | DRD2 (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8597251 | 0.69 | ALOX5 (0.31) | — | |
| SCHEMBL8670556 | 0.68 | ALOX5 (0.32) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8668162 | 0.66 | KDM2B (0.32) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8665484 | 0.66 | KDM4E (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8925600 | 0.65 | CCNE1 (0.37) | — | |
| SCHEMBL8924461 | 0.65 | NPC1 (0.33) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8992121 | 0.64 | BRD4 (0.37) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8824405 | 0.64 | NPC1 (0.34) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |