Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668167 | 0.80 | DRD2 (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL9229702 | 0.74 | HTR1A (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8992121 | 0.72 | BRD4 (0.37) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8924114 | 0.71 | HTR1A (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8922263 | 0.71 | NR1I2 (0.33) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553780 | 0.71 | NPC1 (0.36) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8925600 | 0.70 | CCNE1 (0.37) | DRD2USP2ALDH1A1 | |
| SCHEMBL8603712 | 0.70 | NR1I2 (0.37) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553057 | 0.69 | KMT2A (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553434 | 0.69 | MEN1 (0.36) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |