Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226529 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL13569333 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL15317909 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL7411458 | 0.78 | CTSL (0.46) | SMN1; SMN2LMNAMEN1KMT2ACTSL | |
| SCHEMBL4430842 | 0.77 | LMNA (0.56) | SMN1; SMN2NPC1RAB9ALMNASLC1A3 | |
| SCHEMBL4430839 | 0.77 | LMNA (0.56) | SMN1; SMN2NPC1RAB9ALMNASLC1A3 | |
| SCHEMBL4431806 | 0.77 | LMNA (0.56) | SMN1; SMN2NPC1RAB9ALMNASLC1A3 | |
| SCHEMBL7471592 | 0.76 | LMNA (0.56) | SMN1; SMN2LMNASLC1A3SLC1A1HTT | |
| SCHEMBL7426643 | 0.76 | LMNA (0.55) | SMN1; SMN2LMNASLC1A3SLC1A1HTT | |
| SCHEMBL12879321 | 0.76 | LMNA (0.55) | SMN1; SMN2LMNASLC1A3SLC1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753660-A | Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1998-05-19 | — | — | US | disclosed |