Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780034 | 0.88 | PTGS2 (0.34) | PTGS2EPAS1PTGS1KDM1AVEGFA | |
| SCHEMBL8662439 | 0.79 | PTGS2 (0.38) | PTGS2EPAS1PTGS1VEGFASERPINE1 | |
| SCHEMBL1180312 | 0.78 | PTGS2 (0.35) | PTGS2EPAS1PTGS1KDM1AVEGFA | |
| SCHEMBL8663058 | 0.76 | PTGS2 (0.39) | PTGS2EPAS1PTGS1VEGFAGCGR | |
| SCHEMBL8665112 | 0.75 | EPAS1 (0.41) | EPAS1VEGFAGCGRMAPK14 | |
| SCHEMBL8666733 | 0.75 | EPAS1 (0.39) | PTGS2EPAS1PTGS1GCGRMAPK14 | |
| SCHEMBL9256934 | 0.74 | AHR (0.34) | PTGS2EPAS1PTGS1 | |
| SCHEMBL9254235 | 0.74 | PTGS2 (0.33) | PTGS2GCGRMAPK14 | |
| SCHEMBL8665118 | 0.73 | ALDH1A1 (0.37) | PTGS2EPAS1PTGS1VEGFAKCNH2 | |
| SCHEMBL8664483 | 0.72 | EPAS1 (0.32) | PTGS2EPAS1PTGS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739155-A | Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0549866-B1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID CO (US) | 1997-08-13 | — | — | EP | disclosed |
| US-5484807-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | BASF AKTIENGESELLSCHAFT | 1996-01-16 | — | — | US | disclosed |
| US-5468877-A | FOR PROTECTING CROPS | AMERICAN CYANAMID COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
| US-5306827-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0549866-A1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |