Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257029 | 0.78 | EPAS1 (0.36) | AHREPAS1MEN1HTTKMT2A | |
| SCHEMBL9258502 | 0.75 | AHR (0.36) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL8668183 | 0.74 | PTGS2 (0.35) | EPAS1PTGS2PTGS1 | |
| SCHEMBL9259250 | 0.73 | EPAS1 (0.36) | AHREPAS1MEN1HTTKMT2A | |
| SCHEMBL9258499 | 0.72 | AHR (0.36) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL8799220 | 0.71 | AHR (0.38) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL9339859 | 0.66 | PSD (0.41) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL9227995 | 0.65 | AHR (0.41) | AHRMEN1HTTKMT2AKDM4E | |
| SCHEMBL8780034 | 0.64 | PTGS2 (0.34) | EPAS1PTGS2PTGS1 | |
| SCHEMBL8483151 | 0.63 | AHR (0.42) | AHRMEN1HTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378724-A | Insecticide. miticide, nematocide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| EP-0591806-A1 | Substituted 2-arylpyrroles | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |