Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 6/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779966 | 0.84 | PTGS2 (0.35) | EPAS1PTGS2CHRNA7PTGS1KDM4E | |
| SCHEMBL8662561 | 0.79 | ALDH1A1 (0.40) | EPAS1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8666107 | 0.78 | EPAS1 (0.40) | EPAS1PTGS2MEN1ALDH1A1LMNA | |
| SCHEMBL8663058 | 0.78 | PTGS2 (0.39) | EPAS1PTGS2GCGRMAPK14PTGS1 | |
| SCHEMBL9257029 | 0.76 | EPAS1 (0.36) | EPAS1PTGS2PTGS1KDM4EMEN1 | |
| SCHEMBL9259250 | 0.76 | EPAS1 (0.36) | EPAS1PTGS2PTGS1KDM4EMEN1 | |
| SCHEMBL8668183 | 0.75 | PTGS2 (0.35) | EPAS1PTGS2GCGRMAPK14PTGS1 | |
| SCHEMBL29172448 | 0.74 | GCGR (0.38) | PTGS2GCGRMAPK14PTGS1KDM4E | |
| SCHEMBL8665112 | 0.73 | EPAS1 (0.41) | EPAS1GCGRMAPK14KDM4EMEN1 | |
| SCHEMBL1180312 | 0.73 | PTGS2 (0.35) | EPAS1PTGS2GCGRMAPK14PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484807-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | BASF AKTIENGESELLSCHAFT | 1996-01-16 | — | — | US | claimed |
| JP-6211785-A | — | — | None | — | — | JP | disclosed |
| US-5739155-A | Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 1998-04-14 | — | — | US | disclosed |
| EP-0549866-B1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID CO (US) | 1997-08-13 | — | — | EP | disclosed |
| US-5484807-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | BASF AKTIENGESELLSCHAFT | 1996-01-16 | — | — | US | disclosed |
| US-5468877-A | FOR PROTECTING CROPS | AMERICAN CYANAMID COMPANY (US) | 1995-11-21 | — | — | US | disclosed |
| US-5378724-A | Insecticide. miticide, nematocide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| JP-H06211785-A | SUBSTITUTED 2-ARYLPYRROLES | BAYER AG | 1994-08-02 | — | — | JP | disclosed |
| CN-1086513-A | Substituted 2-arylpyrroles | BAYER AG (DE) | 1994-05-11 | — | — | CN | disclosed |
| US-5306827-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0591806-A1 | Substituted 2-arylpyrroles | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| US-5284863-A | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0549866-A1 | Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-07 | — | — | EP | disclosed |