Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.50 |
| ▸ | PLG | P00747 | 4/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 7/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664984 | 0.89 | F10 (0.58) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL7364906 | 0.85 | GPR119 (0.59) | HRH3CHEK2 | |
| SCHEMBL18672909 | 0.81 | MEN1 (0.56) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL9013886 | 0.77 | CASP6 (0.53) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL16220677 | 0.77 | EPHX2 (0.56) | NAMPTCYP4F2CYP4A11HRH3RORC | |
| SCHEMBL24596887 | 0.76 | CYP4F2 (0.51) | F10PRSS1PRSS2PRSS3SRD5A1 | |
| SCHEMBL2096831 | 0.76 | EPHX2 (0.55) | NAMPTACACBCYP4F2CYP4A11EPHX2 | |
| Hydrochloric Acid SCHEMBL9014030 | 0.76 | CASP6 (0.51) | F10PRSS1PRSS2PRSS3PLG | |
| SCHEMBL31370640 | 0.76 | ALDH1A1 (0.55) | SRD5A1NAMPTCYP4F2CYP4A11HRH3 | |
| SCHEMBL2091338 | 0.75 | EPHX2 (0.57) | SRD5A1NAMPTCYP4F2CYP4A11RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756504-A | TREATMENT OF DYSMENORRHEA, PREVENTION OF PREMATURE LABOR | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5464788-A | Stopping labor | MERCK & CO., INC. (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1995025443-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-09-28 | — | — | WO | disclosed |