Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804427 | 0.88 | CYP2D6 (0.45) | CYP2C19HSD17B10CYP2D6LMNABLM | |
| SCHEMBL7433120 | 0.83 | POLB (0.45) | CYP2C19HSD17B10CYP2D6LMNAMEN1 | |
| SCHEMBL8668373 | 0.83 | LMNA (0.40) | CYP2C19HSD17B10CYP2D6LMNABLM | |
| SCHEMBL7433122 | 0.83 | POLB (0.45) | CYP2C19HSD17B10CYP2D6LMNAMEN1 | |
| SCHEMBL7433127 | 0.83 | POLB (0.45) | CYP2C19HSD17B10CYP2D6LMNAMEN1 | |
| SCHEMBL20835887 | 0.80 | CYP2C19 (0.50) | CYP2C19HSD17B10CYP2D6LMNABLM | |
| SCHEMBL8899635 | 0.80 | RECQL (0.40) | CYP2C19HSD17B10CYP2D6LMNABLM | |
| SCHEMBL10469586 | 0.78 | MEN1 (0.58) | CYP2C19HSD17B10CYP2D6LMNABLM | |
| SCHEMBL21436384 | 0.76 | SIGMAR1 (0.34) | CYP2C19HSD17B10CYP2D6MEN1KMT2A | |
| SCHEMBL8954369 | 0.75 | HSD17B10 (0.46) | CYP2C19HSD17B10CYP2D6LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |