SCHEMBL8668289

SCHEMBL8668289

CC(C)=CCOc1cc(Cl)nc(OCc2ccccc2)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.41
MAOB P27338 6/20 0.41
MAOA P21397 1/20 0.41
PIN1 Q13526 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
MCL1 Q07820 2/20 0.37
ADORA3 P0DMS8 1/20 0.37
ADORA1 P30542 1/20 0.37
BAK1 Q16611 1/20 0.37
NUDT1 P36639 1/20 0.37
ALDH1A1 P00352 1/20 0.36
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36
PTGER1 P34995 1/20 0.36
CNR1 P21554 1/20 0.36
NPC1 O15118 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384805 0.84 PIN1 (0.47) PIN1NUDT1ALDH1A1PTGESALOX5
SCHEMBL8669896 0.83 PIN1 (0.40) PIN1NUDT1ALDH1A1ALOX5PTGER1
SCHEMBL8669771 0.80 ALDH1A1 (0.53) MAOBPIN1RXRARXRBRXRG
SCHEMBL8670167 0.78 PIN1 (0.48) MAOBPIN1ALOX5CNR1NPC1
SCHEMBL8668293 0.77 MCL1 (0.39) MAOBPIN1RXRARXRBRXRG
SCHEMBL8665281 0.74 ALDH1A1 (0.49) PIN1ALDH1A1ALOX5
SCHEMBL4270551 0.73 NUDT1 (0.51) MAOBPIN1NUDT1ALDH1A1PTGES
SCHEMBL6639567 0.71 MPO (0.49) MAOBMAOAPIN1NUDT1ALOX5
SCHEMBL603696 0.71 NUDT1 (0.48) MCL1BAK1NUDT1ALDH1A1PTGES
SCHEMBL12886677 0.71 SMN1; SMN2 (0.38) RXRARXRBRXRGMCL1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723412-A HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
US-5599770-A WEED CONTROL; INCLUDING AN ADJUVANT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
EP-0694538-A2 2-benzyloxy-4-phenoxypyrimidine derivative, processes for producing the derivative and herbicidal composition containing the derivative KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-31 EP disclosed
EP-0692477-A1 Herbicidal compositions containing 2-benzyloxypyrimidine derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-17 EP disclosed