Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536241 | 0.83 | LMNA (0.41) | ALDH1A1MAPTHPGDL3MBTL1KMT2A | |
| SCHEMBL2533235 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDTDP1MAPK1L3MBTL1 | |
| SCHEMBL8127898 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTDP1MAPK1 | |
| SCHEMBL8127809 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDTDP1MAPK1 | |
| SCHEMBL2535686 | 0.78 | TSHR (0.42) | ALDH1A1MAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL27558112 | 0.78 | CHRNB2 (0.56) | ALDH1A1MAPTHPGDTDP1MAPK1 | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDTDP1MAPK1 | |
| Benzyl Dimethylcarbamate SCHEMBL5134244 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDTDP1MAPK1 | |
| SCHEMBL16294301 | 0.76 | RAB9A (0.36) | HPGDKMT2ANPC1RAB9A | |
| Benzyl Dimethylcarbamate SCHEMBL14031385 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |