SCHEMBL8668738

SCHEMBL8668738

CCOc1ccccc1CC(CO)NC(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 2/20 0.52
SYK P43405 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
CYP3A4 P08684 5/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
TSHR P16473 2/20 0.45
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8669583 0.90 CTRB1 (0.49) CTRB1SYKSMN1; SMN2MMEACE
SCHEMBL8669070 0.84 CTRB1 (0.46) CTRB1SYKMEN1KMT2ASMN1; SMN2
SCHEMBL8668099 0.84 MEN1 (0.54) MEN1KMT2ASMN1; SMN2MMEACE
SCHEMBL8612085 0.82 CTRB1 (0.60) CTRB1SMN1; SMN2CYP3A4ALDH1A1CYP1A2
SCHEMBL8612079 0.82 CTRB1 (0.60) CTRB1SMN1; SMN2CYP3A4ALDH1A1CYP1A2
SCHEMBL213314 0.82 SYK (0.64) CTRB1SYKMEN1KMT2ACYP3A4
SCHEMBL2636259 0.82 SYK (0.64) CTRB1SYKMEN1KMT2ACYP3A4
SCHEMBL11528148 0.82 SYK (0.64) CTRB1SYKMEN1KMT2ACYP3A4
SCHEMBL9001816 0.81 CTRB1 (0.50) CTRB1SYKMEN1KMT2ASMN1; SMN2
SCHEMBL9002188 0.81 ALDH1A1 (0.50) CTRB1SYKMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5853699-A Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder SCHERING AKTIENGESELLSCHAFT (DE) 1998-12-29 US disclosed
EP-0794800-A1 USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS SCHERING AKTIENGESELLSCHAFT (DE) 1997-09-17 EP disclosed
WO-1996016678-A1 USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS SCHERING AKTIENGESELLSCHAFT (DE) 1996-06-06 WO disclosed