Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870576 | 1.00 | HSD17B10 (0.47) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL8871032 | 0.87 | ACE (0.46) | FFAR2SIGMAR1ACE | |
| SCHEMBL8829085 | 0.86 | ACE (0.45) | FFAR2POLBSIGMAR1ACEALDH1A1 | |
| SCHEMBL8871068 | 0.85 | ACE (0.47) | FFAR2SIGMAR1ACEMEN1KMT2A | |
| SCHEMBL8829132 | 0.83 | SIGMAR1 (0.48) | SIGMAR1ACEKMT2A | |
| SCHEMBL7663358 | 0.83 | HSD17B10 (0.52) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL8871931 | 0.81 | HTT (0.39) | FFAR2SIGMAR1ACEALDH1A1 | |
| SCHEMBL8668739 | 0.81 | ACE (0.47) | SIGMAR1ACEMEN1ALDH1A1KMT2A | |
| SCHEMBL14024616 | 0.81 | HSD17B10 (0.54) | HSD17B10FFAR2POLBGAARAB9A | |
| SCHEMBL3072035 | 0.81 | HSD17B10 (0.54) | HSD17B10FFAR2POLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |