Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669093 | 0.98 | PTGS2 (0.45) | PTGS2ARL3MBTL1MAPTTSHR | |
| SCHEMBL8668975 | 0.73 | AR (0.41) | ARMAPTTSHRALDH1A1MAPK1 | |
| SCHEMBL8669096 | 0.71 | AR (0.41) | ARMAPTTSHRALDH1A1MAPK1 | |
| SCHEMBL8554048 | 0.70 | PTGS2 (0.39) | PTGS2ARL3MBTL1MAPTTSHR | |
| SCHEMBL8668966 | 0.70 | SMN1; SMN2 (0.38) | PTGS2ARL3MBTL1MAPTALDH1A1 | |
| SCHEMBL24129458 | 0.68 | HPGD (0.61) | ARL3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL8503831 | 0.67 | MAPT (0.39) | ARMAPTTSHRALDH1A1MAPK1 | |
| SCHEMBL6178471 | 0.66 | PTGS2 (0.48) | PTGS2L3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL14380877 | 0.65 | KDR (0.55) | — | |
| SCHEMBL8669816 | 0.65 | AR (0.38) | ARMAPTTSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |