Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552372 | 0.75 | PTGS2 (0.36) | PTGS2HTTTSHRL3MBTL1MAPT | |
| SCHEMBL8669093 | 0.70 | PTGS2 (0.45) | PTGS2TSHRL3MBTL1MAPTAR | |
| SCHEMBL8668972 | 0.70 | PTGS2 (0.45) | PTGS2TSHRL3MBTL1MAPTAR | |
| SCHEMBL9026089 | 0.68 | NOS2 (0.57) | HTTMAPTLMNAKMT2APOLB | |
| SCHEMBL22890912 | 0.65 | TSHR (0.48) | HTTTSHRL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8553294 | 0.65 | S1PR4 (0.33) | — | |
| SCHEMBL8550147 | 0.65 | — | — | |
| SCHEMBL8552692 | 0.64 | TDP1 (0.36) | MAPTALDH1A1 | |
| SCHEMBL8551375 | 0.64 | KDM4E (0.39) | PTGS2HTTTSHRL3MBTL1MAPT | |
| SCHEMBL8551897 | 0.62 | LMNA (0.35) | HTTTSHRMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |