Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670315 | 0.89 | MAPT (0.33) | MEN1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8438828 | 0.88 | KMT2A (0.41) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8672636 | 0.85 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8672641 | 0.85 | TLR8 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8436458 | 0.84 | MAPT (0.48) | KMT2ALMNAMAPK1PDE10APDE2A | |
| SCHEMBL8668302 | 0.83 | CACNA1D (0.35) | MEN1KMT2ATSHRPKM | |
| SCHEMBL8672844 | 0.83 | MAPT (0.30) | MAPT | |
| SCHEMBL8442772 | 0.83 | HTR1D (0.41) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL8670335 | 0.81 | CYP2C9 (0.36) | KMT2ALMNAMAPTNPC1TSHR | |
| SCHEMBL8440207 | 0.81 | NPSR1 (0.36) | MEN1KMT2AMAPK1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |